Forum topic: Modafinil and Buproprion

Mon Jun 30th, 2008 - 12:44am by griwei

Forum: 
Diagnosis and Treatment of ADHD
Using both Modafinil and Buproprion? Diagnosed a little more than a year ago, at 39. Concerta and Adderall both posed dysthymic side effects, even when the latter was paired with Wellbutrin. The Wellbutrin definitely helped impulsiveness too. In Canada, we're still awaiting the newer stimulant formulations. We do have access to Provigil (Alertec), however. I have the psychiatrist's blessing to start a trial while we wait for other stimulant choices, but what I want to know is whether I can keep the Wellbutrin (maybe lowered to 150mg/d from 300mg/d). Anybody familiar with taking both of these drugs for combination ADHD without any comorbid conditions or disorders? I understand that they may interact in a manner so as to increase each others potency, but if I'm starting on the lower 100mcg/d dose of Modafinil and the lower dose of Buproprion, I don't see that as much of a problem. I should mention that my curiosity is led by the fact that the psychiatrist doesn't write the prescriptions. He just sends a letter to my GP and we discuss where to go from there. The green light came last week and the drugs start next week, after a baseline liver number has been established (and I've dropped the Wellbutrin, either to 150/d or zero). Thanks in advance.

Comments

Submitted by Annie (not verified) on Mon Jun 30th, 2008 - 8:46pm

Hello, I take both, WB XL 450 mg & provigil 200 mg, along w/ a cocktail of other meds. WB has been the best for my depression. I have no idea what it has done for the ADD except I've finally stopped "self medicating". When the WB dosage was upped to 450 mg this is when it happened. If I was only able to take 1 med, it would be the WB! Provigil was prescribed because my DR. felt I could not tolerate amphs. i'm 5'9" and only weigh 124#. I've been as low as 113# which is medically anorexic, though I NEVER stopped myself from eating, I just have no appetite. Some people eat when they are sad, I don't feel any hunger. Which came first, the Adhd inattentive or the depression? I remember as far back as 7 yo of depressive thoughts. I was sure I was adopted, because how could my real parents treat me, their child the way the did. I was labeled stupid, lazy, crazy - by them and to all my immediate family and my relatives, I'm the "looser" in the family and it has caused a lifetime of damage to be treated as such. They don't believe in my ADD diagnosis. They think it's another excuse for my behavior(s). They do realize I'm depressed, but offer no support. Things like that aren't talked about, acknowledged in my family. I'm an embarrassment to them. I've recently received SSD (very difficult to get) because of all my problems, so even though I am now very poor (below poverty level) the stress of trying to work, organize, get along with authority figures and co-workers is gone. I tried strattera w/ bad side effects of constant sweating, to the point of soaking thru the waistband of bluejeans. Making a short story long is my forte! Best of luck and hang on to the WB, I take both, and others!!!!!! Annie